Fig. 4
From: Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
CNAs and SNVs/indels in cancer-critical genes. Among genes in the Cancer Gene Census (n = 83 genes included in the targeted sequencing panel, ranked vertically in alphabetical order), simultaneous mutations and CNAs in individual cell lines (grouped horizontally according to genomic phenotypes as indicated) were detected in CRC relevant oncogenes, including KRAS and EGFR, and tumor suppressor genes, including TP53 and APC. The cell line Colo320, which has a neuroendocrine origin, is marked by an asterisk. CNA: copy number aberration, CRC: colorectal cancer, MSI/MSS: microsatellite instable/stable, POLE: POLE mutated, SNV: single nucleotide variant