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Table 1 Relevant disease and signal pathway of binding partners of WBP2

From: WW domain-binding protein 2: an adaptor protein closely linked to the development of breast cancer

Gene

Disease

Signal Pathway

Yes associated protein

Liver cancer [100], prostate carcinoma [101], lung cancer [102], breast cancer [76].

Hippo pathway [103]

Pax8

Morphogenesis of the thyroid gland [20].

Interaction with WBP2

Estrogen receptor

Breast cancer [48]

Wnt pathway [48]

Progesterone receptor

Breast cancer [17]

Interaction with YAP [17]

Rsp5p

Cancer-associated papillomavirus [21]

Ubiquitination pathway [21]

Nedd4

Liddle syndrome [104]

Ubiquitination pathway [83]

TAZ/WWTR1

Breast cancer [24]

Hippo and Wnt pathway [76]

WWOX

Breast cancer [105]

Endocrine pathway [105]