Fig. 3

Progressive breast cancer subtype-specific lncRNA identification and validation. a Hierarchical clustering of differentially expressed genes in breast cancer tissues (N = 15), adjacent normal tissues (N = 15) and normal breast tissue from non-cancer patients (N = 3) via RNA-Seq performed by our research group. Red through blue colour indicates high to low expression levels, respectively. b, c and d RNA-Seq data visualization of TINCR (b) and Linc00511 (c) and PPP1R26-AS1 (d) representing HER-2, triple-negative and luminal B subtype-specific lncRNAs, respectively. e, f and g Validation of TINCR (e), Linc00511 (f) and PPP1R26- AS1 (g) as progressive breast cancer subtype-specific lncRNAs in the TCGA. The expression level of each gene was measured by log2 FPKM. **** P < 0. 0001