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Fig. 5 | Molecular Cancer

Fig. 5

From: MiR-661 promotes tumor invasion and metastasis by directly inhibiting RB1 in non small cell lung cancer

Fig. 5

RB1 interacted with E2F1 and affected EMT process. a. E2F1 protein levels in NSCLC cells and human lung epithelial cells. b. Western blotting of EMT markers in A549 and SPC-A1 cells with E2F1 overexpression. c. Co-immunoprecipitation of RB1 and E2F1 in NSCLC cells. d. E2F1 protein levels in A549 and SPC-A1 with RB1 knockdown. e. E2F1 protein levels in A549 and SPC-A1 with miR-661 overexpression. f. Immunochemistry analysis of E2F1 expression in subcutaneous tumor formed by A549 infected with LV-miR-661 or LV-NC

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Molecular Cancer

ISSN: 1476-4598