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Fig. 5 | Molecular Cancer

Fig. 5

From: FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer

Fig. 5

The oncogenic effect of FOXP3 is mediated by activating Wnt/β-catenin signaling pathway. a The effect of FOXP3 on Wnt/β-catenin signaling pathway was assessed by dual-luciferase reporter assays in A549 and H460 cells. b Knockdown of FOXP3 impaired Topflash reporter activities in A549 cells. c FOXP3 upregulated protein expression of c-Myc and Cyclin D1 in A549 and H460 cells. d FOXP3 upregulated mRNA expression of c-Myc and Cyclin D1 in A549 and H460 cells

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Molecular Cancer

ISSN: 1476-4598