Fig. 4
From: Metformin suppresses cancer initiation and progression in genetic mouse models of pancreatic cancer
Chronic pancreatitis-induced pancreatic fibrosis was decreased following metformin treatment. a Masson’s trichrome staining and immunohistochemical staining of α-SMA. Scale bars: H&E (top row) = 400 μm; (2nd row) = 100 μm; α-SMA (top row) = 400 μm; (2nd row) = 100 μm. b-c Quantification of Masson’s trichrome and α-SMA in mice treated with vehicle, cerulein, cerulein plus metformin. *P < 0.05