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Table 1 Correlation between the clinicopathologic characteristics and CASC2 and miR-367 expression in HCC (n = 75)

From: Long non-coding RNA CASC2 suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells through CASC2/miR-367/FBXW7 axis

Clinical parameters

Cases

Expression level

P value

Expression level

P value

CASC2high (n = 38)

CASC2low (n = 37)

miR-367high (n = 38)

miR-367low (n = 37)

Age(years)

 < 50

24

13

11

0.677

10

14

0.285

 ≥ 50

51

25

26

28

23

Gender

 Male

64

34

30

0.304

32

32

0.781

 Female

11

4

7

6

5

HBV

 Absent

13

9

4

0.141

7

6

0.801

 Present

62

29

33

31

31

Serum AFP level (ng/mL)

 < 400

18

11

7

0.127

6

12

0.092

 ≥ 400

57

27

30

32

25

Tumor size (cm)

 < 5

34

21

13

0.080

12

22

0.015a

 ≥ 5

41

17

24

26

15

Number of tumor nodules

 1

62

35

28

0.104

30

32

0.389

 ≥ 2

13

4

9

8

5

Cirrhosis

 Absent

20

12

8

0.330

7

13

0.102

 Present

55

26

29

31

24

Venous infiltration

 Absent

54

33

21

0.004a

23

31

0.025a

 Present

21

5

16

15

6

Edmondson-Steiner grading

 I + II

49

29

20

0.043a

22

27

0.170

 III + IV

26

9

17

16

10

TNM tumor stage

 I + II

56

34

22

0.003a

24

32

0.020a

 III + IV

19

4

15

14

5

  1. HCC hepatocellular carcinoma, HBV hepatitis B virus, AFP alpha-fetoprotein, TNM tumor-node-metastasis
  2. aStatistically significant