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Fig. 7 | Molecular Cancer

Fig. 7

From: Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas

Fig. 7

Overexpression of NMI suppressed tumor growth in a xenograft mouse model. Human A549 cells transfected respectively with (1) control plasmid (Ctrl), (2) NMI overexpression plasmid (NMI), (3) Ctrl + LPS, (4) NMI + LPS, (5) NMI shRNA + LPS (shRNA + LPS) were injected into the right flank of nude mice (n = 6 per group). a Tumors from the mice after sacrifice. b Representative images of the xenograft-bearing mice. c Tumor volume of each mouse at the time of sacrifice was measured. d Tumor weight of each mouse at the end of the experiment was measured. e Tumor volume of each mouse was recorded every three days during the course of the experiment. f The expression of NMI and COX-2 in xenografts were detected by HE and immunohistochemical staining (400 × magnification)

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