TY - JOUR AU - Ocana, A. AU - Pandiella, A. AU - Siu, L. L. AU - Tannock, I. F. PY - 2010 DA - 2010// TI - Preclinical development of molecular-targeted agents for cancer JO - Nat Rev Clin Oncol VL - 8 UR - https://doi.org/10.1038/nrclinonc.2010.194 DO - 10.1038/nrclinonc.2010.194 ID - Ocana2010 ER - TY - JOUR AU - Atkins, M. B. AU - Larkin, J. PY - 2016 DA - 2016// TI - Immunotherapy combined or sequenced with targeted therapy in the treatment of solid tumors: current perspectives JO - J Natl Cancer Inst VL - 108 UR - https://doi.org/10.1093/jnci/djv414 DO - 10.1093/jnci/djv414 ID - Atkins2016 ER - TY - JOUR AU - Templeton, A. J. AU - McNamara, M. G. AU - Seruga, B. PY - 2014 DA - 2014// TI - Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis JO - J Natl Cancer Inst VL - 106 UR - https://doi.org/10.1093/jnci/dju124 DO - 10.1093/jnci/dju124 ID - Templeton2014 ER - TY - JOUR AU - Soest, R. J. AU - Templeton, A. J. AU - Vera-Badillo, F. E. PY - 2015 DA - 2015// TI - Neutrophil-to-lymphocyte ratio as a prognostic biomarker for men with metastatic castration-resistant prostate cancer receiving first-line chemotherapy: data from two randomized phase III trials JO - Ann Oncol VL - 26 UR - https://doi.org/10.1093/annonc/mdu569 DO - 10.1093/annonc/mdu569 ID - Soest2015 ER - TY - JOUR AU - Templeton, A. J. AU - Knox, J. J. AU - Lin, X. PY - 2016 DA - 2016// TI - Change in Neutrophil-to-lymphocyte ratio in response to targeted therapy for metastatic renal cell carcinoma as a prognosticator and biomarker of efficacy JO - Eur Urol VL - 70 UR - https://doi.org/10.1016/j.eururo.2016.02.033 DO - 10.1016/j.eururo.2016.02.033 ID - Templeton2016 ER - TY - JOUR AU - Jensen, H. K. AU - Donskov, F. AU - Marcussen, N. PY - 2009 DA - 2009// TI - Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma JO - J Clin Oncol VL - 27 UR - https://doi.org/10.1200/JCO.2008.18.9498 DO - 10.1200/JCO.2008.18.9498 ID - Jensen2009 ER - TY - JOUR AU - Bronte, V. AU - Brandau, S. AU - Chen, S. H. PY - 2016 DA - 2016// TI - Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards JO - Nat Commun VL - 7 UR - https://doi.org/10.1038/ncomms12150 DO - 10.1038/ncomms12150 ID - Bronte2016 ER - TY - JOUR AU - Swierczak, A. AU - Mouchemore, K. A. AU - Hamilton, J. A. AU - Anderson, R. L. PY - 2015 DA - 2015// TI - Neutrophils: important contributors to tumor progression and metastasis JO - Cancer Metastasis Rev VL - 34 UR - https://doi.org/10.1007/s10555-015-9594-9 DO - 10.1007/s10555-015-9594-9 ID - Swierczak2015 ER - TY - JOUR AU - Coffelt, S. B. AU - Wellenstein, M. D. AU - Visser, K. E. PY - 2016 DA - 2016// TI - Neutrophils in cancer: neutral no more JO - Nat Rev Cancer VL - 16 UR - https://doi.org/10.1038/nrc.2016.52 DO - 10.1038/nrc.2016.52 ID - Coffelt2016 ER - TY - JOUR AU - Rosenbauer, F. AU - Tenen, D. G. PY - 2007 DA - 2007// TI - Transcription factors in myeloid development: balancing differentiation with transformation JO - Nat Rev Immunol VL - 7 UR - https://doi.org/10.1038/nri2024 DO - 10.1038/nri2024 ID - Rosenbauer2007 ER - TY - JOUR AU - McKinstry, W. J. AU - Li, C. L. AU - Rasko, J. E. PY - 1997 DA - 1997// TI - Cytokine receptor expression on hematopoietic stem and progenitor cells JO - Blood VL - 89 ID - McKinstry1997 ER - TY - JOUR AU - Steinbach, K. H. AU - Schick, P. AU - Trepel, F. PY - 1979 DA - 1979// TI - Estimation of kinetic parameters of neutrophilic, eosinophilic, and basophilic granulocytes in human blood JO - Blutalkohol VL - 39 ID - Steinbach1979 ER - TY - JOUR AU - Hanahan, D. AU - Weinberg, R. A. PY - 2011 DA - 2011// TI - Hallmarks of cancer: the next generation JO - Cell VL - 144 UR - https://doi.org/10.1016/j.cell.2011.02.013 DO - 10.1016/j.cell.2011.02.013 ID - Hanahan2011 ER - TY - JOUR AU - Jamieson, T. AU - Clarke, M. AU - Steele, C. W. PY - 2012 DA - 2012// TI - Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis JO - J Clin Invest VL - 122 UR - https://doi.org/10.1172/JCI61067 DO - 10.1172/JCI61067 ID - Jamieson2012 ER - TY - JOUR AU - Antonio, N. AU - Bonnelykke-Behrndtz, M. L. AU - Ward, L. C. PY - 2015 DA - 2015// TI - The wound inflammatory response exacerbates growth of pre-neoplastic cells and progression to cancer JO - EMBO J VL - 34 UR - https://doi.org/10.15252/embj.201490147 DO - 10.15252/embj.201490147 ID - Antonio2015 ER - TY - JOUR AU - Shojaei, F. AU - Wu, X. AU - Zhong, C. PY - 2007 DA - 2007// TI - Bv8 regulates myeloid-cell-dependent tumour angiogenesis JO - Nature VL - 450 UR - https://doi.org/10.1038/nature06348 DO - 10.1038/nature06348 ID - Shojaei2007 ER - TY - JOUR AU - Shojaei, F. AU - Singh, M. AU - Thompson, J. D. AU - Ferrara, N. PY - 2008 DA - 2008// TI - Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression JO - Proc Natl Acad Sci U S A VL - 105 UR - https://doi.org/10.1073/pnas.0712185105 DO - 10.1073/pnas.0712185105 ID - Shojaei2008 ER - TY - JOUR AU - Fridlender, Z. G. AU - Sun, J. AU - Kim, S. PY - 2009 DA - 2009// TI - Polarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TAN JO - Cancer Cell VL - 16 UR - https://doi.org/10.1016/j.ccr.2009.06.017 DO - 10.1016/j.ccr.2009.06.017 ID - Fridlender2009 ER - TY - JOUR AU - Bodogai, M. AU - Moritoh, K. AU - Lee-Chang, C. PY - 2015 DA - 2015// TI - Immunosuppressive and Prometastatic functions of myeloid-derived suppressive cells rely upon education from tumor-associated B cells JO - Cancer Res VL - 75 UR - https://doi.org/10.1158/0008-5472.CAN-14-3077 DO - 10.1158/0008-5472.CAN-14-3077 ID - Bodogai2015 ER - TY - JOUR AU - Houghton, A. M. AU - Rzymkiewicz, D. M. AU - Ji, H. PY - 2010 DA - 2010// TI - Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth JO - Nat Med VL - 16 UR - https://doi.org/10.1038/nm.2084 DO - 10.1038/nm.2084 ID - Houghton2010 ER - TY - JOUR AU - Finisguerra, V. AU - Conza, G. AU - Matteo, M. PY - 2015 DA - 2015// TI - MET is required for the recruitment of anti-tumoural neutrophils JO - Nature VL - 522 UR - https://doi.org/10.1038/nature14407 DO - 10.1038/nature14407 ID - Finisguerra2015 ER - TY - JOUR AU - Welch, D. R. AU - Schissel, D. J. AU - Howrey, R. P. AU - Aeed, P. A. PY - 1989 DA - 1989// TI - Tumor-elicited polymorphonuclear cells, in contrast to “normal” circulating polymorphonuclear cells, stimulate invasive and metastatic potentials of rat mammary adenocarcinoma cells JO - Proc Natl Acad Sci U S A VL - 86 UR - https://doi.org/10.1073/pnas.86.15.5859 DO - 10.1073/pnas.86.15.5859 ID - Welch1989 ER - TY - JOUR AU - Spiegel, A. AU - Brooks, M. W. AU - Houshyar, S. PY - 2016 DA - 2016// TI - Neutrophils suppress Intraluminal NK cell-mediated tumor cell clearance and enhance Extravasation of disseminated carcinoma cells JO - Cancer Discov VL - 6 UR - https://doi.org/10.1158/2159-8290.CD-15-1157 DO - 10.1158/2159-8290.CD-15-1157 ID - Spiegel2016 ER - TY - JOUR AU - Granot, Z. AU - Henke, E. AU - Comen, E. A. PY - 2011 DA - 2011// TI - Tumor entrained neutrophils inhibit seeding in the premetastatic lung JO - Cancer Cell VL - 20 UR - https://doi.org/10.1016/j.ccr.2011.08.012 DO - 10.1016/j.ccr.2011.08.012 ID - Granot2011 ER - TY - JOUR AU - Qian, B. Z. AU - Li, J. AU - Zhang, H. PY - 2011 DA - 2011// TI - CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis JO - Nature VL - 475 UR - https://doi.org/10.1038/nature10138 DO - 10.1038/nature10138 ID - Qian2011 ER - TY - JOUR AU - Huang, B. AU - Lei, Z. AU - Zhao, J. PY - 2007 DA - 2007// TI - CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers JO - Cancer Lett VL - 252 UR - https://doi.org/10.1016/j.canlet.2006.12.012 DO - 10.1016/j.canlet.2006.12.012 ID - Huang2007 ER - TY - JOUR AU - Kumar, V. AU - Patel, S. AU - Tcyganov, E. AU - Gabrilovich, D. I. PY - 2016 DA - 2016// TI - The nature of myeloid-derived suppressor cells in the tumor microenvironment JO - Trends Immunol VL - 37 UR - https://doi.org/10.1016/j.it.2016.01.004 DO - 10.1016/j.it.2016.01.004 ID - Kumar2016 ER - TY - JOUR AU - Heng, D. Y. AU - Xie, W. AU - Regan, M. M. PY - 2009 DA - 2009// TI - Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study JO - J Clin Oncol VL - 27 UR - https://doi.org/10.1200/JCO.2008.21.4809 DO - 10.1200/JCO.2008.21.4809 ID - Heng2009 ER - TY - JOUR AU - Leibowitz-Amit, R. AU - Templeton, A. J. AU - Omlin, A. PY - 2014 DA - 2014// TI - Clinical variables associated with PSA response to abiraterone acetate in patients with metastatic castration-resistant prostate cancer JO - Ann Oncol VL - 25 UR - https://doi.org/10.1093/annonc/mdt581 DO - 10.1093/annonc/mdt581 ID - Leibowitz-Amit2014 ER - TY - JOUR AU - Templeton, A. J. AU - Pezaro, C. AU - Omlin, A. PY - 2014 DA - 2014// TI - Simple prognostic score for metastatic castration-resistant prostate cancer with incorporation of neutrophil-to-lymphocyte ratio JO - Cancer VL - 120 UR - https://doi.org/10.1002/cncr.28890 DO - 10.1002/cncr.28890 ID - Templeton2014 ER - TY - JOUR AU - Lorente, D. AU - Mateo, J. AU - Templeton, A. J. PY - 2015 DA - 2015// TI - Baseline neutrophil-lymphocyte ratio (NLR) is associated with survival and response to treatment with second-line chemotherapy for advanced prostate cancer independent of baseline steroid use JO - Ann Oncol VL - 26 UR - https://doi.org/10.1093/annonc/mdu587 DO - 10.1093/annonc/mdu587 ID - Lorente2015 ER - TY - JOUR AU - Trellakis, S. AU - Bruderek, K. AU - Dumitru, C. A. PY - 2011 DA - 2011// TI - Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease JO - Int J Cancer VL - 129 UR - https://doi.org/10.1002/ijc.25892 DO - 10.1002/ijc.25892 ID - Trellakis2011 ER - TY - JOUR AU - Wang, J. AU - Jia, Y. AU - Wang, N. PY - 2014 DA - 2014// TI - The clinical significance of tumor-infiltrating neutrophils and neutrophil-to-CD8+ lymphocyte ratio in patients with resectable esophageal squamous cell carcinoma JO - J Transl Med VL - 12 UR - https://doi.org/10.1186/1479-5876-12-7 DO - 10.1186/1479-5876-12-7 ID - Wang2014 ER - TY - JOUR AU - Caruso, R. A. AU - Bellocco, R. AU - Pagano, M. PY - 2002 DA - 2002// TI - Prognostic value of intratumoral neutrophils in advanced gastric carcinoma in a high-risk area in northern Italy JO - Mod Pathol VL - 15 UR - https://doi.org/10.1097/01.MP.0000020391.98998.6B DO - 10.1097/01.MP.0000020391.98998.6B ID - Caruso2002 ER - TY - JOUR AU - Galdiero, M. R. AU - Bianchi, P. AU - Grizzi, F. PY - 2016 DA - 2016// TI - Occurrence and significance of tumor-associated neutrophils in patients with colorectal cancer JO - Int J Cancer VL - 139 UR - https://doi.org/10.1002/ijc.30076 DO - 10.1002/ijc.30076 ID - Galdiero2016 ER - TY - JOUR AU - Waight, J. D. AU - Hu, Q. AU - Miller, A. PY - 2011 DA - 2011// TI - Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0027690 DO - 10.1371/journal.pone.0027690 ID - Waight2011 ER - TY - JOUR AU - Kowanetz, M. AU - Wu, X. AU - Lee, J. PY - 2010 DA - 2010// TI - Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.1015855107 DO - 10.1073/pnas.1015855107 ID - Kowanetz2010 ER - TY - JOUR AU - Bertini, R. AU - Allegretti, M. AU - Bizzarri, C. PY - 2004 DA - 2004// TI - Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury JO - Proc Natl Acad Sci U S A VL - 101 UR - https://doi.org/10.1073/pnas.0402090101 DO - 10.1073/pnas.0402090101 ID - Bertini2004 ER - TY - JOUR AU - Baselga, J. AU - Tabernero, J. M. PY - 2001 DA - 2001// TI - Weekly docetaxel in breast cancer: applying clinical data to patient therapy JO - Oncologist VL - 6 UR - https://doi.org/10.1634/theoncologist.6-suppl_3-26 DO - 10.1634/theoncologist.6-suppl_3-26 ID - Baselga2001 ER - TY - JOUR AU - Stark, M. A. AU - Huo, Y. AU - Burcin, T. L. PY - 2005 DA - 2005// TI - Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17 JO - Immunity VL - 22 UR - https://doi.org/10.1016/j.immuni.2005.01.011 DO - 10.1016/j.immuni.2005.01.011 ID - Stark2005 ER - TY - JOUR AU - Gaffen, S. L. AU - Jain, R. AU - Garg, A. V. AU - Cua, D. J. PY - 2014 DA - 2014// TI - The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing JO - Nat Rev Immunol VL - 14 UR - https://doi.org/10.1038/nri3707 DO - 10.1038/nri3707 ID - Gaffen2014 ER - TY - JOUR AU - Mei, J. AU - Liu, Y. AU - Dai, N. PY - 2012 DA - 2012// TI - Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice JO - J Clin Invest VL - 122 UR - https://doi.org/10.1172/JCI60588 DO - 10.1172/JCI60588 ID - Mei2012 ER - TY - JOUR AU - Ries, C. H. AU - Cannarile, M. A. AU - Hoves, S. PY - 2014 DA - 2014// TI - Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy JO - Cancer Cell VL - 25 UR - https://doi.org/10.1016/j.ccr.2014.05.016 DO - 10.1016/j.ccr.2014.05.016 ID - Ries2014 ER - TY - JOUR AU - Cassier, P. A. AU - Italiano, A. AU - Gomez-Roca, C. A. PY - 2015 DA - 2015// TI - CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study JO - Lancet Oncol VL - 16 UR - https://doi.org/10.1016/S1470-2045(15)00132-1 DO - 10.1016/S1470-2045(15)00132-1 ID - Cassier2015 ER - TY - JOUR AU - Wculek, S. K. AU - Malanchi, I. PY - 2015 DA - 2015// TI - Neutrophils support lung colonization of metastasis-initiating breast cancer cells JO - Nature VL - 528 UR - https://doi.org/10.1038/nature16140 DO - 10.1038/nature16140 ID - Wculek2015 ER - TY - JOUR AU - Highfill, S. L. AU - Cui, Y. AU - Giles, A. J. PY - 2014 DA - 2014// TI - Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy JO - Sci Transl Med VL - 6 UR - https://doi.org/10.1126/scitranslmed.3007974 DO - 10.1126/scitranslmed.3007974 ID - Highfill2014 ER - TY - JOUR AU - Kim, K. AU - Skora, A. D. AU - Li, Z. PY - 2014 DA - 2014// TI - Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells JO - Proc Natl Acad Sci U S A VL - 111 UR - https://doi.org/10.1073/pnas.1410626111 DO - 10.1073/pnas.1410626111 ID - Kim2014 ER - TY - JOUR AU - Chung, A. S. AU - Wu, X. AU - Zhuang, G. PY - 2013 DA - 2013// TI - An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy JO - Nat Med VL - 19 UR - https://doi.org/10.1038/nm.3291 DO - 10.1038/nm.3291 ID - Chung2013 ER - TY - JOUR AU - Coffelt, S. B. AU - Visser, K. E. PY - 2015 DA - 2015// TI - Immune-mediated mechanisms influencing the efficacy of anticancer therapies JO - Trends Immunol VL - 36 UR - https://doi.org/10.1016/j.it.2015.02.006 DO - 10.1016/j.it.2015.02.006 ID - Coffelt2015 ER -