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Fig. 1 | Molecular Cancer

Fig. 1

From: Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca2+-permeable Cationic Channel in lung carcinoma cells

Fig. 1

PLPP4 is upregulated in lung carcinoma. a PLPP1-7 expression levels in the RNA sequencing profiles of 57 paired lung adenocarcinoma (ADC) tissues from TCGA dataset. b PLPP1-7 expression levels in the RNA sequencing profile of 51 paired lung squamous cell carcinoma (SQC) tissues from TCGA dataset. c Expression of PLPP4 in the adjacent normal tissues (ANT), ADC tissues and SQC tissues in TCGA lung carcinoma profiles. d Expression of PLPP4 in the adjacent normal tissues (ANT), ADC tissues and SQC tissues in the lung carcinoma profiles from ArrayExpress. e PLPP4 expression was upregulated in the RNA sequencing profile of 57 ADC tissues from TCGA dataset compared with that in ANT. f PLPP4 expression was upregulated in the RNA sequencing profile of 51 SQC tissues from TCGA dataset compared with that in ANT. g and h mRNA and protein expression levels of PLPP4 in eight paired lung tissues, including 5 paired ADC tissues, 2 paired SQC tissues and 1 lung adenosquamous carcinoma tissues (Mix). α-Tubulin was used as a loading control. The average PLPP4 mRNA expression level was normalized to the expression of GAPDH. Each bar represents the mean values ± SD of three independent experiments. *P < 0.05

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