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Fig. 6 | Molecular Cancer

Fig. 6

From: Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca2+-permeable Cationic Channel in lung carcinoma cells

Fig. 6

PLPP4 silencing inhibits the tumorigenesis and lung colonization of lung carcinoma cells in vivo. a Images of excised tumors from six BALB/c mice at 30 days after injection with the indicated cells. b Average weight of excised tumors from the indicated mice. Each bar represents the median values ± quartile values. *P < 0.05. c Tumor volumes were measured every five days. Each bar represents the median values ± quartile values. d and e In vivo lung metastasis assays of A549 cells with PLPP4 knockdown. Lung metastases in mice were confirmed by H&E staining. The number of lung tumor nests in each group was counted under a low power field (LPF) and is presented as the median values ± quartile values (right panel). *P < 0.05. f Kaplan-Meier survival curves of the indicated mice

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Molecular Cancer

ISSN: 1476-4598