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Fig. 5 | Molecular Cancer

Fig. 5

From: Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression

Fig. 5

Identification and characteristics of circLARP4 in GC cells. a CircRNA microarray chip was used to identify the differentially expressed circRNAs between GC and adjacent normal tissues. b The genomic loci of the LATP4 gene and circLARP4. Arrows represent divergent primers that bind to the genomic region of circLARP4. c qRT-PCR analysis of circLARP4 and LARP4 RNA after treatment with RNase R in HGC-27 and MKN-28 cells. d qRT-PCR analysis of circLARP4 and LARP4 RNA after treatment with Actinomycin D at the indicated time points in HGC-27 and MKN-28 cells. e qRT-PCR analysis of circLARP4 and LARP4 RNA in the cytoplasm or the nucleus in HGC-27 and MKN-28 cells. e The expression level of circLARP4 was decreased in GC tissues compared the normal tissues. f The cellular localization of circLARP4 in GC tissue cells and adjacent normal tissue cells. The nuclei were stained with DAPI for blue color, and the cytoplasmic circLARP4 was stained for green color

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Molecular Cancer

ISSN: 1476-4598