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Fig. 9 | Molecular Cancer

Fig. 9

From: Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression

Fig. 9

Schematic representation of the proposed mechanism of circLARP4 in GC cells. circLARP4 acted as a miR-424 sponge to regulate the miR-424/LATS1/YAP pathway in GC cells. Decreased circLARP4 expression in GC increased the activity of miR-424, which downregulated the expression of LATS1 and upregulated LATS1 downstream effector, thereby promoting gastric tumorigenesis and progression

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