Fig. 1
From: Cell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancer
The alterations of the TMEM16A gene in cBioPortal database. a TMEM16A gene was examined in 29 studies with >100 human cancer samples and >5% gene alterations. The copy number alteration (CNA) occurs more frequently in cancer. b TMEM16A missense mutations identified in cBioPortal database. A total of 165 missense mutations are shown. The most frequent mutations are R561L/Q/W, R433Q, and R588G/Q