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Fig. 1 | Molecular Cancer

Fig. 1

From: miR-92b-3p acts as a tumor suppressor by targeting Gabra3 in pancreatic cancer

Fig. 1

Reduced miR-92b-3p expression levels were found in PC tissues and cell lines. a qPCR analyses of the expression levels of miR-92b-3p in 46 fresh PC and CNP tissues. b ISH analyses of miR-92b-3p expression levels in 82 FFPE PC and CNP tissues. c Representative images of the ISH staining analyses of 82 FFPE PC and CNP tissues using the anti-miR-92b-3p probe. Scale bars: 50 μm. d Comparison of miR-92b-3p expression levels in the PC cell lines with those in normal pancreatic epithelial cells by qPCR. e-g Association analyses of miR-92b-3p expression levels and tumor size, lymph node metastasis and TNM stage. h Kaplan-Meier analyses of postoperative survival in PC patients stratified by miR-92b-3p levels. The P value was assessed by log-rank test. RNU6B snRNA was used to normalize the qPCR results. Bar, SEM; *P < 0.05; **P < 0.01; ***P < 0.001; Student’s t test

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