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Fig. 5 | Molecular Cancer

Fig. 5

From: A novel mechanism of lncRNA and miRNA interaction: CCAT2 regulates miR-145 expression by suppressing its maturation process in colon cancer cells

Fig. 5

CCAT2 blocks cleavage of pri- and pre-miR-145 in vitro. The qRT-PCR results showing pri-, pre- and mature miR-145 levels following recombinant Dicer reaction containing the total RNAs isolated from either CCAT2 overexpressing or CCAT2-KO (a) CR-HT-29 or (b) HCT-116 cells. All the data represent means ± SEM, *P < 0.001, compared to the control

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