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Table 1 qRT-PCR showing the relative levels of pri-, pre- and mature miR-145. The reaction mixture contained synthesized pri-miR-145 and total RNAs isolated from CR-HT-29 or HCT-116 CCAT2 overexpressing or CCAT2-KO cells, and corresponding controls digested with Dicer

From: A novel mechanism of lncRNA and miRNA interaction: CCAT2 regulates miR-145 expression by suppressing its maturation process in colon cancer cells

 

Pri-

Pre-

Mature

HCT-116 Cells:

   

 Control

1

0.14

613.11

 CCAT2

1

0.61

0.18

 KO/CCAT2

1

0.08

215.27

CR-HT-29 Cells:

   

 Control

1

0.29

0.65

 CCAT2

1

0.16

0.07

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Molecular Cancer

ISSN: 1476-4598