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Fig. 2 | Molecular Cancer

Fig. 2

From: A long non-coding RNA HOTTIP expression is associated with disease progression and predicts outcome in small cell lung cancer patients

Fig. 2

HOTTIP may regulate SCLC cell proliferation and cell cycle. a A pcDNA3.1-HOTTIP expression vector was transfected successfully into H69 and H446 cells, respectively. b HOTTIP RNAi sequences were transfected into H146 and H446AR cells, respectively. c CCK8 assay was used to detect the effect of HOTTIP on SCLC cell proliferation after HOTTIP overexpression. d CCK8 assay was used to detect the effect of HOTTIP on SCLC cell proliferation after HOTTIP knockdown. e & f Flow-cytometric analysis was used for cell cycle detection after HOTTIP knockdown in H446AR and H146 cells. g & h Flow-cytometric analysis was used for cell cycle detection after HOTTIP overexpression in H446 and H69 cells. *, P < 0.05; **, P < 0.01

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