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Fig. 5 | Molecular Cancer

Fig. 5

From: A long non-coding RNA HOTTIP expression is associated with disease progression and predicts outcome in small cell lung cancer patients

Fig. 5

Further experiments confirmed the ceRNA role of HOTTIP. a & b & c Co-transfection dual luciferase reporter assay was used to demonstrate the ceRNA role of HOTTIP. d & e RNA pull-down and SDS-page assay showed HOTTIP may interact with Ago2 protein. f RIP experiments showed that Ago2 had a function in the formation of HOTTIP and miR574-5p complex and in their regulation of EZH1. *, P < 0.05; **, P < 0.01

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Molecular Cancer

ISSN: 1476-4598