Fig. 5
From: Monitoring multiple myeloma by idiotype-specific peptide binders of tumor-derived exosomes
Tumor progression and serum exosomes production in tumor-engrafted mice. a Kaplan-Meier survival curves in 5T33MM-engrafted mice (n = 10), A20-engrafted mice (n = 10) and un-grafted control mice (n = 10). b Determination of serum paraprotein (IgG2b) concentration in 5T33MM- or A20-engrafted mice and control mice measured by ELISA. c Flow cytometric analysis of Red-Exo-stained exosomes derived from serum of a representative 5T33MM-engrafted mouse incubated with FITC-conjugated p5 peptide. d Flow cytometric analysis of Red-Exo-stained exosomes derived from serum of a representative A20-engrafted mouse incubated with FITC-conjugated p5 peptide