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Fig. 3 | Molecular Cancer

Fig. 3

From: Dysregulated long noncoding RNAs (lncRNAs) in hepatocellular carcinoma: implications for tumorigenesis, disease progression, and liver cancer stem cells

Fig. 3

Mechanism of lncRNA function. lncRNAs are involved in HCC development through multiple mechanisms. (1) At the epigenetic level, lncRNAs can regulate the expression of target genes via recruiting chromatin modifying factors to alter chromatin structure [42]; (2) lncRNAs can control the process of alternative splicing [41]; (3) lncRNAs can regulate mRNA stability [41]; (4) lncRNAs can act as competing endogenous RNAs (ceRNAs) [47]

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Molecular Cancer

ISSN: 1476-4598