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Fig. 6 | Molecular Cancer

Fig. 6

From: LncRNA RP11-436H11.5, functioning as a competitive endogenous RNA, upregulates BCL-W expression by sponging miR-335-5p and promotes proliferation and invasion in renal cell carcinoma

Fig. 6

Deregulation of lncRNA RP11-436H11.5 suppresses RCC cell proliferation and invasion in RCC orthotopic xenografts. a, b and c. Representative IVIS images of tumor size (a), macroscopic appearance (b) and metastasis (c) in shlncRNA RP11-436H11.5 group vs control group. d, e and f. Representative IVIS images of tumor size (d), macroscopic appearance (e) and metastasis (f) in oelncRNA RP11-436H11.5 group vs control group. g, h and i. Representative macroscopic appearance and IVIS image of metastatic foci (white arrows) in lung (g), liver (h) and spleen (i). j. Representative macroscopic appearances of metastatic foci (white arrows) in diaphragm. b and e. Each sample was run in triplicate and in multiple experiments for mean ± SEM. *P < 0.05 compared to controls

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Molecular Cancer

ISSN: 1476-4598