TY - JOUR AU - Torre, L. A. AU - Bray, F. AU - Siegel, R. L. AU - Ferlay, J. AU - Lortet-Tieulent, J. AU - Jemal, A. PY - 2015 DA - 2015// TI - Global cancer statistics, 2012 JO - CA Cancer J Clin VL - 65 UR - https://doi.org/10.3322/caac.21262 DO - 10.3322/caac.21262 ID - Torre2015 ER - TY - JOUR AU - Li, Z. AU - Kang, Y. PY - 2016 DA - 2016// TI - Emerging therapeutic targets in metastatic progression: a focus on breast cancer JO - Pharmacol Ther VL - 161 UR - https://doi.org/10.1016/j.pharmthera.2016.03.003 DO - 10.1016/j.pharmthera.2016.03.003 ID - Li2016 ER - TY - JOUR AU - Ibrahim, M. F. AU - Mazzarello, S. AU - Shorr, R. AU - Vandermeer, L. AU - Jacobs, C. AU - Hilton, J. PY - 2015 DA - 2015// TI - Should de-escalation of bone-targeting agents be standard of care for patients with bone metastases from breast cancer? A systematic review and meta-analysis JO - Ann Oncol VL - 26 UR - https://doi.org/10.1093/annonc/mdv284 DO - 10.1093/annonc/mdv284 ID - Ibrahim2015 ER - TY - JOUR AU - Tanaka, R. PY - 2016 DA - 2016// TI - Risk factors for developing skeletal-related events in breast cancer patients with bone metastases undergoing treatment with bone-modifying agents JO - Oncologist VL - 21 UR - https://doi.org/10.1634/theoncologist.2015-0377 DO - 10.1634/theoncologist.2015-0377 ID - Tanaka2016 ER - TY - JOUR AU - Valastyan, S. AU - Weinberg, R. A. PY - 2011 DA - 2011// TI - Tumor metastasis: molecular insights and evolving paradigms JO - Cell VL - 147 UR - https://doi.org/10.1016/j.cell.2011.09.024 DO - 10.1016/j.cell.2011.09.024 ID - Valastyan2011 ER - TY - JOUR AU - Weilbaecher, K. N. AU - Guise, T. A. AU - McCauley, L. K. PY - 2011 DA - 2011// TI - Cancer to bone: a fatal attraction JO - Nat Rev Cancer VL - 11 UR - https://doi.org/10.1038/nrc3055 DO - 10.1038/nrc3055 ID - Weilbaecher2011 ER - TY - JOUR AU - Esposito, M. AU - Kang, Y. PY - 2014 DA - 2014// TI - Targeting tumor-stromal interactions in bone metastasis JO - Pharmacol Ther VL - 141 UR - https://doi.org/10.1016/j.pharmthera.2013.10.006 DO - 10.1016/j.pharmthera.2013.10.006 ID - Esposito2014 ER - TY - JOUR AU - Putoczki, T. AU - Ernst, M. PY - 2010 DA - 2010// TI - More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancer JO - J Leukoc Biol VL - 88 UR - https://doi.org/10.1189/jlb.0410226 DO - 10.1189/jlb.0410226 ID - Putoczki2010 ER - TY - JOUR AU - Johnstone, C. N. AU - Chand, A. AU - Putoczki, T. L. AU - Ernst, M. PY - 2015 DA - 2015// TI - Emerging roles for IL-11 signaling in cancer development and progression: focus on breast cancer JO - Cytokine Growth Factor Rev VL - 26 UR - https://doi.org/10.1016/j.cytogfr.2015.07.015 DO - 10.1016/j.cytogfr.2015.07.015 ID - Johnstone2015 ER - TY - JOUR AU - McCoy, E. M. AU - Hong, H. AU - Pruitt, H. C. AU - Feng, X. PY - 2013 DA - 2013// TI - IL-11 produced by breast cancer cells augments osteoclastogenesis by sustaining the pool of osteoclast progenitor cells JO - BMC Cancer VL - 13 UR - https://doi.org/10.1186/1471-2407-13-16 DO - 10.1186/1471-2407-13-16 ID - McCoy2013 ER - TY - JOUR AU - Browne, G. AU - Taipaleenmäki, H. AU - Stein, G. S. AU - Stein, J. L. AU - Lian, J. B. PY - 2014 DA - 2014// TI - MicroRNAs in the control of metastatic bone disease JO - Trends Endocrinol Metab VL - 25 UR - https://doi.org/10.1016/j.tem.2014.03.014 DO - 10.1016/j.tem.2014.03.014 ID - Browne2014 ER - TY - JOUR AU - Vimalraj, S. AU - Miranda, P. J. AU - Ramyakrishna, B. AU - Selvamurugan, N. PY - 2013 DA - 2013// TI - Regulation of breast cancer and bone metastasis by microRNAs JO - Dis Markers VL - 35 UR - https://doi.org/10.1155/2013/451248 DO - 10.1155/2013/451248 ID - Vimalraj2013 ER - TY - JOUR AU - Lagos-Quintana, M. AU - Rauhut, R. AU - Yalcin, A. AU - Meyer, J. AU - Lendeckel, W. AU - Tuschl, T. PY - 2002 DA - 2002// TI - Identification of tissue-specific microRNAs from mouse JO - Curr Biol VL - 12 UR - https://doi.org/10.1016/S0960-9822(02)00809-6 DO - 10.1016/S0960-9822(02)00809-6 ID - Lagos-Quintana2002 ER - TY - JOUR AU - Åkerblom, M. AU - Jakobsson, J. PY - 2014 DA - 2014// TI - MicroRNAs as neuronal fate determinants JO - Neuroscientist VL - 20 UR - https://doi.org/10.1177/1073858413497265 DO - 10.1177/1073858413497265 ID - Åkerblom2014 ER - TY - JOUR AU - Sonntag, K. C. AU - Woo, T. U. AU - Krichevsky, A. M. PY - 2012 DA - 2012// TI - Converging miRNA functions in diverse brain disorders: a case for miR-124 and miR-126 JO - Exp Neurol VL - 235 UR - https://doi.org/10.1016/j.expneurol.2011.11.035 DO - 10.1016/j.expneurol.2011.11.035 ID - Sonntag2012 ER - TY - JOUR AU - Furuta, M. AU - Kozaki, K. I. AU - Tanaka, S. AU - Arii, S. AU - Imoto, I. AU - Inazawa, J. PY - 2010 DA - 2010// TI - miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma JO - Carcinogenesis VL - 31 UR - https://doi.org/10.1093/carcin/bgp250 DO - 10.1093/carcin/bgp250 ID - Furuta2010 ER - TY - JOUR AU - Wilting, S. M. AU - van Boerdonk, R. A. AU - Henken, F. E. AU - Meijer, C. J. AU - Diosdado, B. AU - Meijer, G. A. PY - 2010 DA - 2010// TI - Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer JO - Mol Cancer VL - 9 UR - https://doi.org/10.1186/1476-4598-9-167 DO - 10.1186/1476-4598-9-167 ID - Wilting2010 ER - TY - JOUR AU - Vázquez, I. AU - Maicas, M. AU - Marcotegui, N. AU - Conchillo, A. AU - Guruceaga, E. AU - Roman-Gomez, J. PY - 2010 DA - 2010// TI - Silencing of hsa-miR-124 by EVI1 in cell lines and patients with acute myeloid leukemia JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.1011540107 DO - 10.1073/pnas.1011540107 ID - Vázquez2010 ER - TY - JOUR AU - Xia, J. AU - Wu, Z. AU - Yu, C. AU - He, W. AU - Zheng, H. AU - He, Y. PY - 2012 DA - 2012// TI - miR-124 inhibits cell proliferation in gastric cancer through down-regulation of SPHK1 JO - J Pathol VL - 227 UR - https://doi.org/10.1002/path.4030 DO - 10.1002/path.4030 ID - Xia2012 ER - TY - JOUR AU - Sun, Y. AU - Zhao, X. AU - Zhou, Y. AU - Hu, Y. PY - 2012 DA - 2012// TI - miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect JO - Oncol Rep VL - 28 UR - https://doi.org/10.3892/or.2012.1958 DO - 10.3892/or.2012.1958 ID - Sun2012 ER - TY - JOUR AU - Wang, P. AU - Chen, L. AU - Zhang, J. AU - Chen, H. AU - Fan, J. AU - Wang, K. PY - 2014 DA - 2014// TI - Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1 JO - Oncogene VL - 33 UR - https://doi.org/10.1038/onc.2012.598 DO - 10.1038/onc.2012.598 ID - Wang2014 ER - TY - JOUR AU - Shi, X. B. AU - Xue, L. AU - Ma, A. H. AU - Tepper, C. G. AU - Gandour-Edwards, R. AU - Kung, H. J. PY - 2013 DA - 2013// TI - Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells JO - Oncogene VL - 32 UR - https://doi.org/10.1038/onc.2012.425 DO - 10.1038/onc.2012.425 ID - Shi2013 ER - TY - JOUR AU - Lv, X. B. AU - Jiao, Y. AU - Qing, Y. AU - Hu, H. AU - Cui, X. AU - Lin, T. PY - 2011 DA - 2011// TI - miR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro JO - Chin J Cancer VL - 30 UR - https://doi.org/10.5732/cjc.011.10289 DO - 10.5732/cjc.011.10289 ID - Lv2011 ER - TY - JOUR AU - Liang, Y. J. AU - Wang, Q. Y. AU - Zhou, C. X. AU - Yin, Q. Q. AU - He, M. AU - Yu, X. T. PY - 2013 DA - 2013// TI - MiR-124 targets slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer JO - Carcinogenesis VL - 34 UR - https://doi.org/10.1093/carcin/bgs383 DO - 10.1093/carcin/bgs383 ID - Liang2013 ER - TY - JOUR AU - Han, Z. B. AU - Yang, Z. AU - Chi, Y. AU - Zhang, L. AU - Wang, Y. AU - Ji, Y. PY - 2013 DA - 2013// TI - MicroRNA-124 suppresses breast cancer cell growth and motility by targeting CD151 JO - Cell Physiol Biochem VL - 31 UR - https://doi.org/10.1159/000350100 DO - 10.1159/000350100 ID - Han2013 ER - TY - JOUR AU - Li, L. AU - Luo, J. AU - Wang, B. AU - Wang, D. AU - Xie, X. AU - Yuan, L. PY - 2013 DA - 2013// TI - Microrna-124 targets flotillin-1 to regulate proliferation and migration in breast cancer JO - Mol Cancer VL - 12 UR - https://doi.org/10.1186/1476-4598-12-163 DO - 10.1186/1476-4598-12-163 ID - Li2013 ER - TY - JOUR AU - Feng, T. AU - Shao, F. AU - Wu, Q. AU - Zhang, X. AU - Xu, D. AU - Qian, K. PY - 2016 DA - 2016// TI - miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation JO - Oncotarget VL - 7 ID - Feng2016 ER - TY - JOUR AU - Zhang, F. AU - Wang, B. AU - Long, H. AU - Yu, J. AU - Li, F. AU - Hou, H. PY - 2016 DA - 2016// TI - Decreased miR-124-3p expression prompted breast cancer cell progression mainly by targeting Beclin-1 JO - Clin Lab VL - 62 ID - Zhang2016 ER - TY - JOUR AU - Dong, L. L. AU - Chen, L. M. AU - Wang, W. M. AU - Zhang, L. M. PY - 2015 DA - 2015// TI - Decreased expression of microRNA-124 is an independent unfavorable prognostic factor for patients with breast cancer JO - Diagn Pathol VL - 10 UR - https://doi.org/10.1186/s13000-015-0257-5 DO - 10.1186/s13000-015-0257-5 ID - Dong2015 ER - TY - JOUR AU - Ng, P. K. AU - Tsui, S. K. AU - Lau, C. P. AU - Wong, C. H. AU - Wong, W. H. AU - Huang, L. PY - 2010 DA - 2010// TI - CCAAT/enhancer binding protein beta is up-regulated in giant cell tumor of bone and regulates RANKL expression JO - J Cell Biochem VL - 110 ID - Ng2010 ER - TY - JOUR AU - Zhou, W. AU - Yin, H. AU - Wang, T. AU - Liu, T. AU - Li, Z. AU - Yan, W. PY - 2014 DA - 2014// TI - MiR-126-5p regulates osteolysis formation and stromal cell proliferation in giant cell tumor through inhibition of PTHrP JO - Bone VL - 66 UR - https://doi.org/10.1016/j.bone.2014.06.021 DO - 10.1016/j.bone.2014.06.021 ID - Zhou2014 ER - TY - JOUR AU - Hollensen, A. K. AU - Bak, R. O. AU - Haslund, D. AU - Mikkelsen, J. G. PY - 2013 DA - 2013// TI - Suppression of microRNAs by dual-targeting and clustered tough decoy inhibitors JO - RNA Biol VL - 10 UR - https://doi.org/10.4161/rna.23543 DO - 10.4161/rna.23543 ID - Hollensen2013 ER - TY - JOUR AU - Ho, S. N. AU - Hunt, H. D. AU - Horton, R. M. AU - Pullen, J. K. AU - Pease, L. R. PY - 1989 DA - 1989// TI - Site-directed mutagenesis by overlap extension using the polymerase chain reaction JO - Gene VL - 77 UR - https://doi.org/10.1016/0378-1119(89)90358-2 DO - 10.1016/0378-1119(89)90358-2 ID - Ho1989 ER - TY - JOUR AU - Joung, Y. H. AU - Darvin, P. AU - Kang, D. Y. AU - Sp, N. AU - Byun, H. J. AU - Lee, C. H. PY - 2016 DA - 2016// TI - Methylsulfonylmethane inhibits RANKL-induced osteoclastogenesis in BMMs by suppressing NF-κB and STAT3 activities JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0159891 DO - 10.1371/journal.pone.0159891 ID - Joung2016 ER - TY - JOUR AU - Pivetta, E. AU - Scapolan, M. AU - Pecolo, M. AU - Wassermann, B. AU - Abu-Rumeileh, I. AU - Balestreri, L. PY - 2011 DA - 2011// TI - MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases JO - Breast Cancer Res VL - 13 UR - https://doi.org/10.1186/bcr3047 DO - 10.1186/bcr3047 ID - Pivetta2011 ER - TY - JOUR AU - Lee, Y. AU - Kim, H. J. AU - Park, C. K. AU - Kim, Y. G. AU - Lee, H. J. AU - Kim, J. Y. PY - 2013 DA - 2013// TI - MicroRNA-124 regulates osteoclast differentiation JO - Bone VL - 56 UR - https://doi.org/10.1016/j.bone.2013.07.007 DO - 10.1016/j.bone.2013.07.007 ID - Lee2013 ER - TY - JOUR AU - Irelli, A. AU - Cocciolone, V. AU - Cannita, K. AU - Zugaro, L. AU - Di Staso, M. AU - Lanfiuti Baldi, P. PY - 2016 DA - 2016// TI - Bone targeted therapy for preventing skeletal-related events in metastatic breast cancer JO - Bone VL - 87 UR - https://doi.org/10.1016/j.bone.2016.04.006 DO - 10.1016/j.bone.2016.04.006 ID - Irelli2016 ER - TY - STD TI - Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Coleman R, Powles T, Paterson A, Gnant M, Anderson S, et al. Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials. Lancet. 2015;386:1353–1361. ID - ref38 ER - TY - JOUR AU - Hadji, P. AU - Coleman, R. E. AU - Wilson, C. AU - Powles, T. J. AU - Clézardin, P. AU - Aapro, M. PY - 2016 DA - 2016// TI - Adjuvant bisphosphonates in early breast cancer: consensus guidance for clinical practice from a European panel JO - Ann Oncol VL - 27 UR - https://doi.org/10.1093/annonc/mdv617 DO - 10.1093/annonc/mdv617 ID - Hadji2016 ER - TY - JOUR AU - Girasole, G. AU - Passeri, G. AU - Jilka, R. L. AU - Manolagas, S. C. PY - 1994 DA - 1994// TI - Interleukin-11: a new cytokine critical for osteoclast development JO - J Clin Invest VL - 93 UR - https://doi.org/10.1172/JCI117130 DO - 10.1172/JCI117130 ID - Girasole1994 ER - TY - JOUR AU - Manolagas, S. C. PY - 1995 DA - 1995// TI - Role of cytokines in bone resorption JO - Bone VL - 17 UR - https://doi.org/10.1016/8756-3282(95)00180-L DO - 10.1016/8756-3282(95)00180-L ID - Manolagas1995 ER - TY - JOUR AU - Aubin, J. E. AU - Bonnelye, E. PY - 2000 DA - 2000// TI - Osteoprotegerin and its ligand: a new paradigm for regulation of osteoclastogenesis and bone resorption JO - Osteoporos Int VL - 11 UR - https://doi.org/10.1007/s001980070028 DO - 10.1007/s001980070028 ID - Aubin2000 ER - TY - JOUR AU - Kudo, O. AU - Sabokbar, A. AU - Pocock, A. AU - Itonaga, I. AU - Fujikawa, Y. AU - Athanasou, N. A. PY - 2003 DA - 2003// TI - Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism JO - Bone VL - 32 UR - https://doi.org/10.1016/S8756-3282(02)00915-8 DO - 10.1016/S8756-3282(02)00915-8 ID - Kudo2003 ER - TY - JOUR AU - Sotiriou, C. AU - Lacroix, M. AU - Lespagnard, L. AU - Larsimont, D. AU - Paesmans, M. AU - Body, J. J. PY - 2001 DA - 2001// TI - Interleukins-6 and −11 expression in primary breast cancer and subsequent development of bone metastases JO - Cancer Lett VL - 169 UR - https://doi.org/10.1016/S0304-3835(01)00524-9 DO - 10.1016/S0304-3835(01)00524-9 ID - Sotiriou2001 ER - TY - JOUR AU - Hanavadi, S. AU - Martin, T. A. AU - Watkins, G. AU - Mansel, R. E. AU - Jiang, W. G. PY - 2006 DA - 2006// TI - Expression of interleukin 11 and its receptor and their prognostic value in human breast cancer JO - Ann Surg Oncol VL - 13 UR - https://doi.org/10.1245/ASO.2006.05.028 DO - 10.1245/ASO.2006.05.028 ID - Hanavadi2006 ER - TY - JOUR AU - Cheang, M. C. AU - Chia, S. K. AU - Voduc, D. AU - Gao, D. AU - Leung, S. AU - Snider, J. PY - 2009 DA - 2009// TI - Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer JO - J Natl Cancer Inst VL - 101 UR - https://doi.org/10.1093/jnci/djp082 DO - 10.1093/jnci/djp082 ID - Cheang2009 ER -