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Fig. 2 | Molecular Cancer

Fig. 2

From: HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma

Fig. 2

HSP90 expression was positively correlated with PKM2 expression in HCC tissues. a IHC staining of HSP90 and PKM2 in HCC tissues and the adjacent non-tumor tissues were performed. HSP90 and PKM2 expression in HCC tissues were increased compared with non-tumor tissues. HCC tissues with high HSP90 level showed increased PKM2 protein level compared with those with low HSP90 level. b Compared with tissues with negative HSP90 expression, positive rate of PKM2 was significantly increased in HCC tissues with positive HSP90 expression. c HSP90 IHC scores in HCC tissues were positively correlated with the IHC scores of PKM2. *, P < 0.05 by Chi-square test and Pearson correlation analysis

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Molecular Cancer

ISSN: 1476-4598