Skip to main content
Fig. 9 | Molecular Cancer

Fig. 9

From: HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma

Fig. 9

The prognostic value of HSP90 and PKM2 for HCC patients. HCC patients were divided into HSP90 positive group and HSP90 negative group based on IHC staining. Patients with positive expression of HSP90 had significant shorter (a) overall survival (OS) and (b) disease free survival (DFS). HCC patients were divided into PKM2 positive group and PKM2 negative group based on IHC staining. Patients with positive expression of PKM2 had obvious poorer (c) OS and (d) DFS. HCC patients were divided into four groups: HSP90postivePKM2postive group, HSP90postive PKM2negative group, HSP90negativePKM2postive group and HSP90negativePKM2negative group. HCC patients in HSP90negativePKM2negative group had the best (e) OS and (f) DFS while those in HSP90postivePKM2postive group had the lowest (e) OS and (f) DFS. *, P < 0.05 by Log-rank test

Back to article page