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Fig. 4 | Molecular Cancer

Fig. 4

From: MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer

Fig. 4

Expression of APC is often decreased and inversely correlated with miR-494 expression in human CRC tissues. a Immunohistochemical staining of APC in tumor tissue and corresponding normal colonic epithelium. Normal epithelium shows vesicular brown cytoplasmic APC staining. This staining is nearly absent in the tumor tissue. b APC mRNA expression is frequently decreased in tumor tissues when compared to the matched non-cancerous tissues, as evaluated by real-time PCR. c The relative levels of miR-494 expression were plotted against the relative levels of APC mRNA expression

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