Fig. 6
From: MiR-25-3p promotes the proliferation of triple negative breast cancer by targeting BTG2
Inhibition of BTG2 expression accounted for function of miR-25-3p in TNBC. a. BTG2 protein expression level was measured by western blot. b, c. cell proliferation of Sum-1315 and ZR-751 cells transfected with GV272 empty construct (miR-NC), miR-25-3p inhibitor lentivirus (miR-inhibitor) and BTG2 interfering RNA (siBTG2),miR-25-3p mimics lentivirus (miR-mimics) and BTG2 lentiviral vector(lv-BTG2) was determined by CCK-8 and colony formation assay. d. The cell apoptosis of Sum-1315 and ZR-751 cells after cotransfection was measured in flow cytometry analysis. *p < 0.05, **p < 0.01. The data expressed as the mean ± SD