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Fig. 1 | Molecular Cancer

Fig. 1

From: The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells

Fig. 1

Characterization of CCFs. a Morphology of CCFs, SFs and CCA cells. Original magnification of 40×. b Immunocytochemical staining of CK19, VIM and ASMA. The KKU-213 CCA cell line was used as a positive control of CK1 expression. Original magnification of 400×. c The effect of CCFs-CMs and SFs-CMs on migration of CCA cells in a wound healing assay. At 3, 6, 12, and 18 h, the % of wound area was measured. Bars represent mean ± SD of three measurements. *P < 0.05 (compared to 10% FBS DMEM). #P < 0.05 (compared to SF_CM). d The effect of CCFs-CMs and SFs-CMs on proliferation of CCA cells. Bars represent mean ± SD of two measurements

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