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Fig. 1 | Molecular Cancer

Fig. 1

From: Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis

Fig. 1

Pedigrees of the families with BUB1 and BUB3 mutations. Filled symbol, cancer. Ages at information gathering or at death (†), when available, are indicated on the top-right corner, and ages at cancer diagnosis, between brackets after tumor type. Abbreviations: AP, adenomatous polyp; HP, hyperplastic polyp; JP, juvenile polyp; ca, cancer; CRC, colorectal cancer; PTC, papillary thyroid cancer; N.C., normal colonoscopy; MUT, mutation carrier; WT (wildtype); non-carrier of the mutation identified in the family

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