Table 5 MiRNA-based therapeutics to target tumor angiogenesis
From: New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications
miRNAs | Delivery systems | Cancer | Targets | Ref |
|---|---|---|---|---|
miR-125b | PEI | lung cancer, colorectal cancer | VE-cadherin | [85] |
miR-192 | DOPC | ovarian cancer, renal tumor | EGR1, HOXB9 | [116] |
miR-200 | DOPC | lung cancer, ovarian cancer, renal cancer | IL8, CXCL1 | [117] |
miR-520d | DOPC | ovarian cancer | EphA2 | [118] |
miR-132 | cRGD | breast cancer | p120RasGAP | [86] |
miR-499 | APRPG-PEG | colorectal cancer | VEGF | [122] |
miR-29a/c | CMVs | gastric cancer | VEGF | [127] |
miR-150 | CMVs | sarcoma | VEGF | [128] |