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Fig. 1 | Molecular Cancer

Fig. 1

From: Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

Fig. 1

Cir-ITCH was significantly decreased in BCa and correlated with prognosis of BCa patients. a and b Relative expression level of cir-ITCH in BCa tissues (T) and adjacent normal tissues (N) (a: n = 72, b: n = 59) using qRT-PCR. cir-ITCH expression was significantly lower in bladder cancer tissues, compared with that in adjacent normal tissues (*P < 0.05, Student’s t-test). c Relative expression level of in bladder cancer cell lines and SV-HUC cell using qRT-PCR. d qRT-PCR confirmed the over-expression of cir-ITCH in BCa cell lines EJ and T24 after transfection (*P < 0.05, **P < 0.01, Student’s t-test). e Kaplan-Meier plotter analysis of the correlation of circ-ITCH expression level with overall survival of BCa patients

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Molecular Cancer

ISSN: 1476-4598