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Fig. 3 | Molecular Cancer

Fig. 3

From: Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

Fig. 3

Cir-ITCH induced cell cycle arrest and cell apoptosis in BCa cells. a Representative images of the cell cycle analysis using flow cytometry. b Cir-ITCH arrested the EJ and T24 cell cycle at the G1/S phase, while miR-17 and miR-224 turned the G1/S transition. c Representative images of Annexin V and 7-AAD staining apoptosis assay in EJ and T24 cells. d and e Apoptosis assay showed that increased the rate of apoptosis in EJ and T24 cells. Data are the means ± SEM of three experiments, (*P < 0.05, **P < 0.01, Student’s t-test)

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Molecular Cancer

ISSN: 1476-4598