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Fig. 1 | Molecular Cancer

Fig. 1

From: Role and targeting of anaplastic lymphoma kinase in cancer

Fig. 1

Structure of ALK protein. The human ALK protein is a polypeptid of 1620 amino acid. The ALK mature protein is a classical receptor tyrosine kinase that comprises an extracellular ligand-binding domain, a transmembrane domain, and an intracellular tyrosine kinase domain which harbors the 3-tyrosine motif (Tyr1278, Tyr1282 and Tyr1283) which represents the major auto-phosphorylation site regulating kinase activity

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