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Table 1 Top miRNAs regulated by the PI3K inhibitor LY294002

From: miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer

Rank

miRNAs

Fold change (log2)1

adjusted p-value

1

hsa-miR-100-5p

−2.30

2.15E-38

2

hsa-miR-125b-5p

−2.23

3.40E-36

3

hsa-miR-205-5p

−1.67

5.63E-21

4

hsa-miR-19a-3p2

−1.59

2.28E-14

5

hsa-miR-18a-5p2

−1.57

2.28E-14

6

hsa-miR-181a-5p

1.56

8.78E-13

7

hsa-miR-503-5p

−1.44

7.17E-11

8

hsa-miR-19b-3p2

−1.43

1.50E-14

9

hsa-miR-196b-5p

−1.25

6.66E-07

10

hsa-let-7b-5p

−1.14

1.73E-09

11

hsa-miR-372-3p

−1.12

1.25E-01

12

hsa-miR-9-5p

−1.05

3.65E-08

13

hsa-miR-20a-5p + hsa-miR-20b-5p2

−1.04

3.65E-08

14

hsa-miR-422a

−1.02

1.38E-05

15

hsa-miR-1180-3p

−1.02

6.77E-07

16

hsa-miR-374a-5p

−1.02

1.48E-07

17

hsa-miR-99b-5p

−1.01

3.42E-06

  1. 1Fold change relative to DMSO treated cells. Cut off was set to ±0.4 log2FC (n = 3)
  2. 2OncomiR-1 cluster