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Fig. 2 | Molecular Cancer

Fig. 2

From: Novel targeted therapies and immunotherapy for advanced thyroid cancers

Fig. 2

Tumor immune surveillance and host early response to tumor microenvironment: The lack of MHC I on tumor cells activates Natural killer cells. Dendritic cells present tumor antigens to cytotoxic T cells which exhibit a cytotoxic activity on dividing malignant cells. Note in tumor surveillance phase that tumor associated macrophages (TAM) present in tumor microenvironment are of anti-tumoral M1 phenotype and also the expressed cytokines in the medium are of immune stimulatory type

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