Fig. 2
From: Role of the HGF/c-MET tyrosine kinase inhibitors in metastasic melanoma
Downstream signaling interactions of the HGF/c-MET signaling pathway. Abbreviations: ERK/MAPK - extracellular signal-regulated kinase/mitogen-activated protein kinases; STAT - signal transducer and activator of transcription factor; GRB2- growth factor receptor-bound protein 2; GAB1, GRB2-associated binding protein 1; PLCy - phospholipase C; PI3K - phosphoinositol 3-kinase; Akt - protein kinase B; mTOR - mammalian target of rapamycin