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Fig. 1 | Molecular Cancer

Fig. 1

From: Advances in studies of tyrosine kinase inhibitors and their acquired resistance

Fig. 1

Cell signaling pathways induced by RTK. RTK can bind to ligands and phosphorylate tyrosine residues of target proteins and transmit information through PI3K/AKT/mTOR; RAS/RAF/MEK/ERK; PLCγ/PKC and other signaling pathways to activate a series of biochemical reactions; or different information combined to cause a comprehensive cellular response, including cell proliferation, cell migration and tumor formation

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