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Fig. 1 | Molecular Cancer

Fig. 1

From: Clinical significance of plasma cell-free DNA mutations in PIK3CA, AKT1, and ESR1 gene according to treatment lines in ER-positive breast cancer

Fig. 1

Kaplan-Meier plots of the association of the presence of cfDNA PIK3CA mutations with RFS; a and BCSS; b in the entire cohort and the presence of cfDNA PIK3CA mutations with TTF in less than the 5th line; c more than the 5th line; d, and the presence of cfDNA ESR1 mutations with TTF in less than the 5th line; e and more than the 5th line; f in the entire cohort. The presence of cfDNA PIK3CA mutations and cfDNA ESR1 mutations were defined as either positive or negative. Abbreviations: cfDNA, cell-free DNA; RFS, relapse-free survival; BCSS, breast cancer-specific survival; TTF, time to treatment failure

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