Table 1 Correlation between exosomal HOTTIP and clinicopathological parameters of gastric cancer (n = 126)
Features | Number of cases | Exosomal HOTTIP levels | P value |
|---|---|---|---|
Age (years) | |||
< 60 | 61 | 2.348 (1.607–3.061) | 0.1340 |
≥ 60 | 65 | 2.020 (1.423–2.891) | |
Gender | |||
Female | 60 | 2.194 (1.837–3.109) | 0.0919 |
Male | 66 | 2.166 (1.333–2.837) | |
Tumor size (cm) | |||
< 5 | 63 | 1.995 (1.412–2.840) | 0.1051 |
≥ 5 | 63 | 2.409 (1.826–3.039) | |
Pathological differention | |||
Well + moderate | 57 | 1.997 (1.573–3.164) | 0.8273 |
Poor | 69 | 2.419 (1.458–2.921) | |
Invasion depth | |||
T1 + T2 + T3 | 78 | 2.109 (1.515–2.609) | 0.0298* |
T4 | 48 | 2.665 (1.535–4.269) | |
Lymph nodes metastasis | |||
Negative | 49 | 2.020 (1.508–2.973) | 0.4204 |
Positive | 77 | 2.348 (1.664–2.944) | |
TNM stage | |||
I and II | 55 | 1.624 (1.316–2.066) | < 0.001*** |
III and IV | 71 | 2.782 (2.219–3.361) | |