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Fig. 3 | Molecular Cancer

Fig. 3

From: The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

Fig. 3

MACC1-AS1 promotes GC cell viability under metabolic stress. a-b MTT and colony formation assays showing that overexpression of MACC1-AS1 promoted cell viability with glucose deprivation; ***P < 0.001. c Western blotting results showing that MACC1-AS1 decreases the expression of bax and cleaved caspase 3 in MKN45. d-e EdU cell proliferation assays showing that MACC1-AS1 promoted cell viability in MKN45 following 12 h of culture in glucose-free medium; *P < 0.05. f-g Flow cytometry results showing that MACC1-AS1 inhibited apoptosis induced by glucose deprivation for 12 h in MKN45; *P < 0.05. h-i Flow cytometry results showing that MACC1-AS1 alleviated glucose deprivation-derived S phrase block

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Molecular Cancer

ISSN: 1476-4598