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Fig. 5 | Molecular Cancer

Fig. 5

From: Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer

Fig. 5

Knockdown of Linc00659 expression with siRNA suppressed HCT116 cell growth. a The expression levels of Linc00659 in eight colon cancer cell lines and adjacent normal tissues were showed. The expression levels of adjacent normal mucosal tissue were obtained from Fig. 2e. b The expression levels of Linc00659 were examined after transfection of HCT116 cells with siRNA. c and d After transient transfection of HCT116 cells with si-Linc00659, cell proliferation and colony formation assays were performed: e graph illustrating quantified values from the colon formation assays. f The anchorage-independent growth of HCT116 with si-Linc00659 transfection was examined by a soft agar formation assay: g graph illustrating quantified values from the assay. Data are reported as the number of colonies relative to the control (mean ± standard deviation). siRNA, small interfering RNA

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Molecular Cancer

ISSN: 1476-4598