Table 1 Summary of lncRNAs regulate cytoskeletons in cancer

Dreh

Intermediate filament

Prevent cancer cell migration through changing the cytoskeleton structure and cell morphology

[34]

LINC00152

F-actin

LINC00152 affects F-actin by regulating the expression of GOLPH3

[41, 45]

LOC344887, CCAT2, HOTAIR

Vimentin

LOC344887, CCAT2 and HOTAIR regulate the expression of vimentin

[32, 55, 57]

PTCSC2

MYH9

PTCSC2 binds MYH9 to regulate cytoskeleton

[59]

GAS5

cofilin

GAS5 suppressed glioma cell growth, migration and invasion by targeting miR-222. miR-222 induced cofilin dephosphorylation by silencing PLXNC1 gene

[61]

UCA1

FSCN1

UCA1 promotes bladder cancer cell migration and invasion by the hsa-miR-145–ZEB1/2– FSCN1 pathway

[66]