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Fig. 5 | Molecular Cancer

Fig. 5

From: LncRNA MT1JP functions as a ceRNA in regulating FBXW7 through competitively binding to miR-92a-3p in gastric cancer

Fig. 5

LncRNA MT1JP regulate FBXW7 expression by sponging miR-92a-3p. a miR-92a-3p significantly reduced luciferase activity in FBXW7-wild not in FBXW7-mut. b Compared with adjacent normal tissues, FBXW7 was remarkably upregulated in GC tissue. c Spearman-Pearson correlation between lncRNA MT1JP and FBXW7 expression in GC tissues (Spearman r = 0.452, P < 0.001). d Western blotting analysis of FBXW7 in BGC-823 and SGC-7901 cells with overexpression of lncRNA MT1JP and/or miR-92a-3p mimics and/or miR-92a-3p inhibitor

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