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Fig. 2 | Molecular Cancer

Fig. 2

From: Tumor-originated exosomal lncUEGC1 as a circulating biomarker for early-stage gastric cancer

Fig. 2

Expression pattern and stability testing of exosomal lncUEGC1 and lncUEGC2 in EGC specimens and GCCs. (a and b) qPCR analysis of the relative plasma exosomal lncUEGC1 (a) and lncUEGC2 (b) levels in stage I and II GC patients (n = 51) and healthy controls (n = 60). (c and d) qPCR analysis of the relative exosomal lncUEGC1 (c) and lncUEGC2 (d) levels in GCC (n = 12) and HPSEC (n = 4) culture media. (e and f) qPCR analysis of the relative plasma circulating lncUEGC1 (e) and lncUEGC2 (f) levels in stage I GC patient plasma samples (n = 20) treated with or without RNase (2 μg/ml) for 20 min. (g and h) Positive correlations between plasma exosomal and plasma circulating lncUEGC1 (g) and lncUEGC2 (h) expression in stage I GC patients (n = 20) were determined using Pearson’ s correlation test (r and P values are shown in the graphs). Differences with P < 0.05 were considered statistically significant

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