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Fig. 1 | Molecular Cancer

Fig. 1

From: Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non–small cell lung cancer cell proliferation by epigenetically repressing p21 expression

Fig. 1

Relative AFAP1-AS1 expression in NSCLC tissues and its clinical significance. a Relative expression levels of AFAP1-AS1 in NSCLC tissues (n = 92) compared with corresponding non-tumor tissues (n = 92). AFAP1-AS1 expression was examined using qPCR and was normalized to GAPDH expression. The △Ct value was determined by subtracting the GAPDH Ct value from the AFAP1-AS1 Ct value Smaller △Ct values indicate higher expression. b AFAP1-AS1 expression was significantly higher in patients with higher pathological stages (III/IV) than in those with lower pathological stages (I/II). c AFAP1-AS1 expression was significantly higher in patients with larger tumor sizes (> 3 cm) than in those with smaller tumor sizes (≤3 cm). d Kaplan-Meier overall survival (OS) curves according to AFAP1-AS1 expression levels. e AFAP1-AS1 expression in NSCLC tissues in TCGA database. *, P < 0.05, and **, P < 0.01

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Molecular Cancer

ISSN: 1476-4598