Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non–small cell lung cancer cell proliferation by epigenetically repressing p21 expression

Table 1 The clinic-pathological factors of 92 NSCLC patients

Characteristics	Numbers	Expression of AFAP1-AS1		p value*
Characteristics	Numbers	low(N = 46)	high(N = 46)	p value*
Sex				0.402
male	42	23	19
female	50	23	27
Age				0.835
≤60	45	22	23
> 60	47	24	23
Histological grade				0.179
Middle or low	75	35	40
high	17	11	6
Histological classification				0.532
SCC (Squamous cell carcinoma)	47	25	22
AD (adenocarcinoma or other)	45	21	24
TNM stage				0.182
Iand II	62	34	28
III and IV	30	12	18
Lymph node metastasis				0.529
negative	41	22	19
positive	51	24	27
Tumor size				< 0.001**
≤3 cm	36	28	8
> 3 cm	56	18	38
History of smoking				0.144
Ever	49	28	21
Never	43	18	25

ISSN: 1476-4598