From: Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer
Protein name | Â | TIGAR | Â | Â | Met | ||||
---|---|---|---|---|---|---|---|---|---|
Characteristics | All cases | Low | High | P-value | Â | All cases | Low | High | P-value |
Participants | 72 | 35 | 37 | Â | Â | 72 | 49 | 23 | Â |
Age | Â | Â | Â | 0.7538 | Â | Â | Â | Â | 0.3726 |
< 65 | 46 | 23 | 23 |  |  | 46 | 33 | 13 |  |
≥65 | 26 | 12 | 14 |  |  | 26 | 16 | 10 |  |
Sex | Â | Â | Â | 0.5040 | Â | Â | Â | Â | 0.4921 |
Female | 26 | 14 | 12 | Â | Â | 26 | 19 | 7 | Â |
Male | 46 | 21 | 25 | Â | Â | 46 | 30 | 16 | Â |
TNM stage | Â | Â | Â | 0.0190 | Â | Â | Â | Â | 0.0012 |
I | 29 | 20 | 9 | Â | Â | 29 | 27 | 2 | Â |
II | 18 | 8 | 10 | Â | Â | 18 | 11 | 7 | Â |
III | 14 | 5 | 9 | Â | Â | 14 | 7 | 7 | Â |
IV | 11 | 2 | 9 | Â | Â | 11 | 4 | 7 | Â |
Nodes metastasis | Â | Â | Â | 0.0005 | Â | Â | Â | Â | 0.0001 |
N0 | 45 | 29 | 16 | Â | Â | 45 | 38 | 7 | Â |
N1–3 | 27 | 6 | 21 |  |  | 27 | 11 | 16 |  |
Distant metastasis | Â | Â | Â | 0.0283 | Â | Â | Â | Â | 0.0143 |
M0 | 61 | 33 | 28 | Â | Â | 61 | 45 | 16 | Â |
M1 | 11 | 2 | 9 | Â | Â | 11 | 4 | 7 | Â |
Cancer progression | Â | Â | Â | 0.0260 | Â | Â | Â | Â | 0.0625 |
No | 33 | 18 | 15 | Â | Â | 33 | 24 | 9 | Â |
Yes | 21 | 5 | 16 | Â | Â | 21 | 10 | 11 | Â |