The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma

Table 1 Correlation between lncRNA PTTG3P expression and clinicopathological characteristics in 90 HCC patients (cohort 2)

Features	All cases	lncRNA PTTG3P expression		^aP value
Features	All cases	Low	High	^aP value
Total number	90	28	62
Age				0.327
> 55	39	10	29
≤55	51	18	33
Gender				1.000
Male	75	23	52
Female	15	5	10
Liver cirrhosis				0.123
with	33	7	26
without	57	21	36
Tumor size(cm)				0.011*
> 5	53	11	42
≤5	37	17	20
Tumor number				1.000
solitary	84	26	58
multiple	6	2	4
Edmondson grade				0.550
I + II	57	19	38
III	33	9	24
TNM stage				0.003*
I + II	43	20	23
III + IV	47	8	39

^aFor analysis of correlation between lncRNA PTTG3P levels and clinical features, Pearson’s chi-square tests were used. When the expected count of variable was less than 5, Fisher’s exact tests was used. *, P < 0 .05

ISSN: 1476-4598