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Fig. 6 | Molecular Cancer

Fig. 6

From: RETRACTED ARTICLE: Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer

Fig. 6

PTAF overexpression leads to OVCAR-3 cell migration and invasion by regulating miR-25. Wound-healing a and migration assays b showed that PTAF promoted OVCAR-3 cell migration, which was inhibited by forced expression of miR-25. n = 5 independent experiments. *P < 0.05, **P < 0.01. c A Transwell invasion assay showed that PTAF promoted OVCAR-3 cell invasion by regulating miR-25. n = 5 independent experiments. **P < 0.01. Wound-healing d and migration assays e showed that silencing of PTAF inhibited TGF-β1-driven migration in OVCAR-3 cells, which was abated by miR-25 knockdown. n = 5 independent experiments. *P < 0.05, **P < 0.01. f A Transwell invasion assay showed that knockdown of PTAF inhibited TGF-β1-induced OVCAR-3 cell invasion. n = 5 independent experiments. *P < 0.05, **P < 0.01

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Molecular Cancer

ISSN: 1476-4598