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Fig. 3 | Molecular Cancer

Fig. 3

From: RETRACTED ARTICLE: LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis

Fig. 3

Detection of GFP-LC3 puncta with or without regulation of PVT1. a, b Representative images of GFP-LC3 puncta in PVT1-overexpressed cells (Capan-2 and MIA PaCa-2) (a) and PVT1-downregulated cells (SW1990 and HPAF-II) (b); c, d Quantitation of GFP-LC3 puncta in PVT1-overexpressed cells (Capan-2 and MIA PaCa-2) (c) and PVT1-downregulated cells (SW1990 and HPAF-II) (d). Enhanced expression remarkably increased the number of GFP-LC3 puncta. Meanwhile, down-regulation of PVT1 decreased the number of GFP-LC3 puncta. Data are presented as the mean ± S.D. (n = 3). * P < 0.05 and ** P < 0.01 by Student’s t-test

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